An experimental gene-editing therapy has produced substantial and lasting reductions in dangerous blood fats after only a single treatment, offering early evidence that CRISPR technology could eventually transform how some severe cholesterol disorders are treated. Researchers from the Cleveland Clinic reported that a one-time infusion of the experimental therapy CTX310...
Republicans Expand Midterm War Chest as Once-Safe House Districts Draw New Attention
Republicans are directing substantial new campaign money into dozens of U.S. House districts that had previously attracted little outside spending, as internal polling prompts the party to broaden its defensive strategy ahead of the November 3 midterm elections. Seemingly, major Republican organizations and megadonors have begun spending in at least...
California Supreme Court Orders Sheriff to Return 650,000 Ballots After Unlawful Election Seizure
The California Supreme Court has unanimously ordered Riverside County Sheriff Chad Bianco to return approximately 650,000 ballots that his department seized during an investigation into alleged voting irregularities, ruling that the operation violated state election law. The September 24 decision resolves a major legal confrontation over who has the authority...
McDonald’s Launches $8.5 Billion Reinvention as Competition and Changing Customers Challenge Its Fast-Food Empire
McDonald’s is preparing one of the largest transformations in its recent history, committing $8.5 billion over the next decade to strengthen its franchise restaurants, modernize operations and adapt its menu as competition intensifies and consumers become increasingly selective about where they spend their money. The investment is part of a...
AI Turns the Computer Science Dream Into a Tough Job Hunt for a New Generation of Graduates
For years, computer science was considered one of the safest paths from college into a well-paid career. Technology companies competed aggressively for young programmers, graduates often received multiple offers, and universities rapidly expanded their computer science programs. Artificial intelligence is now helping overturn that equation. New computer science graduates are...
U.S. Accelerates Shift Away From Animal Testing as AI and Human-Based Models Reshape Drug Research
The U.S. Department of Health and Human Services is accelerating a major transformation in biomedical research, launching new initiatives intended to reduce reliance on animal testing while expanding the use of human cells, organoids, organs-on-chips, artificial intelligence and computational models in drug development. The effort represents one of the federal...
U.S. Seeks $30 Billion Aviation Overhaul After Major Failures Expose Aging Air Traffic System
The Trump administration is preparing to ask Congress for another $30 billion to modernize the U.S. aviation system, dramatically expanding an effort to replace aging air-traffic-control technology after a series of failures disrupted thousands of flights and exposed vulnerabilities in critical national infrastructure. Transportation Secretary Sean Duffy said the additional...
Los Angeles Needs Thousands of Apartments, but Developers Say Building Them No Longer Pays
Los Angeles is confronting a striking contradiction in its housing crisis: the city desperately needs more apartments, but many developers say constructing them has become financially unattractive. Despite persistent housing shortages and high rents, multifamily construction is slowing as developers confront elevated interest rates, falling apartment values, rising construction expenses,...
U.S. Expands Its Arctic Military Footprint in Landmark Greenland Security Deal
The United States, Denmark and Greenland have signed a major new security agreement that significantly expands the American military presence on Greenland while leaving sovereignty over the strategically important Arctic territory unchanged. The agreement represents an effort to resolve months of diplomatic tension generated by President Donald Trump’s repeated demands...
Meta’s Massive Network Gives Zuckerberg the Freedom to Fail Until the Next Big Idea Works
Mark Zuckerberg has survived a remarkable series of expensive technological bets, controversies and strategic mistakes, yet Meta continues to emerge with new opportunities for growth. The latest example is Muse, the company’s new artificial-intelligence assistant, whose rapid popularity demonstrates Meta’s greatest competitive advantage: an enormous global network that gives the...