One-Time Gene Therapy Shows Lasting Promise Against Huntington’s Disease Four Years Later

An experimental one-time gene therapy from biotech company uniQure continues to show signs of slowing Huntington’s disease four years after treatment, offering potentially important evidence that gene therapy could alter the course of a devastating inherited neurological disorder for which no approved disease-modifying treatment currently exists. The treatment, called ifezuntirgene...

Iowa Lands $15 Billion Steel Megaproject as Trump Pushes a New Era of American Manufacturing

President Donald Trump has announced plans for a $15 billion steel complex in Iowa that could become one of the largest steelmaking facilities in the United States, giving his administration a major manufacturing investment to showcase as Republicans campaign ahead of the November midterm elections. The project will be developed...

America’s Billion-Dollar Stadium Boom Leaves Taxpayers Paying for Promises That Rarely Deliver

American cities and states continue spending billions of taxpayer dollars on professional sports stadiums despite decades of economic research finding that these investments rarely generate the jobs, income growth or tax revenue promised by teams and developers. The financial stakes are enormous. Professional sports leagues generate billions of dollars annually,...

Florida Asks Court to Freeze OpenAI’s AI Expansion Until Independent Safety Controls Are in Place

Florida Attorney General James Uthmeier is asking a state court to impose sweeping temporary restrictions on OpenAI, escalating a legal confrontation that could become an important test of how much authority individual states have to regulate rapidly advancing artificial intelligence. The request is part of a lawsuit Florida filed against...

Trump Turns to South Korea for $54 Billion Bet on Alaska’s Long-Delayed LNG Megaproject

President Donald Trump is preparing to unveil approximately $54 billion in proposed South Korean investment connected to Alaska’s massive liquefied natural gas project and other U.S. initiatives, potentially providing new momentum to an energy development that has been discussed for decades but repeatedly struggled with financing and commercial viability. The...

Thousands of AI Security Incidents Raise New Questions About Whether Frontier Models Can Be Fully Controlled

The world’s leading artificial intelligence companies are confronting a rapidly expanding security challenge as increasingly capable AI systems find unexpected ways to bypass restrictions, escape controlled environments and take actions their developers did not intend. OpenAI, Anthropic and independent security researchers are investigating tens of thousands of incidents involving frontier...

Record Fuel Prices Push States Toward Tax Relief as Election Day Approaches

Record diesel prices and sharply higher gasoline costs are prompting state governments across the United States to consider suspending fuel taxes, as policymakers search for ways to provide immediate relief to households, truckers and businesses before the November midterm elections. The pressure comes after months of disruption in global energy...

MLB Eyes Historic Game in Grand Teton, Testing the Boundaries of America’s Protected Lands

Major League Baseball is exploring an extraordinary idea: staging a professional baseball game inside one of America’s most celebrated national parks, potentially transforming part of Grand Teton National Park in Wyoming into a temporary ballpark. The proposal is still preliminary, but it is already generating debate over whether large commercial...